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Preparing for IVF – diagnostics, the procedure, and important tests to make the best from an IVF cycle #IVFWEBINARS

How to prepare for IVF? What tests should be done? What does the procedure look like? Find out from our webinar – watch the video recording of our webinar titled “Preparing for IVF – diagnostics, the procedure, and important tests to make the best from an IVF cycle”. The webinar topic was presented by Dr. Juan Manuel Moreno, Director of the Embryology Laboratory at the Reproduction Unit of Clínica Vistahermosa in Alicante.

You can also view the recording on our YouTube channel. Subscribe to EggDonationFriends YT channel and hit the notification button, and you will receive notifications each time a new webinar recording is up on our channel. If you wish to remain anonymous during our live event’s Q&A session, please use a nickname when registering for our events.

Preparing for IVF – Questions and Answers

Question:

What do you think about using embryo glue in case of implantation failure? Is it effective?

Answer:

Embryo glue doesn’t help implantation. It’s something that we use in our clinics as a standard in every treatment as it helps. It’s like a viscous liquid that we use in the place for the deposition of the embryo but it has nothing to do with implantation. It has to do with a better use and an improvement in the process of the culture.

Question:

I’ve had a failed IVF with ICSI with fresh eggs. My doctor recommended endometrium scratch with the 2nd cycle. Not sure if I should go ahead with it as it costs extra. What’s your opinion?

Answer:

Nowadays there is no scientific or medical evidence that endometrium scratch improves implantation. Anyway, most clinics—and we can include ourselves—do it because our aim is to do all we can to help the implantation. So, should you have it? We think that, yes, you should.

Question:

I’m a healthy 32-year-old woman. However, after 2 years of trying we ended up in two IVF cycles with 14 and 10 eggs. Unfortunately, they could not be fertilized. The embryologist explained the next day that they had abnormal morphology—cytoplasmic halo like cytoplasm which could be seen after denudation and could not be fertilized with ICSI or IVF. What could be wrong with our eggs?

Answer:

According to the doctor’s experience, the most important thing that you need to know when you want to fertilize the eggs is if they are mature or not—especially if you are going to do an ICSI because the IVF can be done with any egg but ICSI can be done only with mature eggs. Only 20% of eggs, once they have been retrieved and we know if they are mature or not, are considered perfect but this is not what we need to take as a starting point. What we do need to take a starting point is to check if the eggs are mature and if so, you need to fertilize all of them. Then if the fertilisation rate it not good then you can think about not doing another technique or improving the matureness of the eggs in another cycle but if you have 14 or 10 eggs you need to check which ones are mature and these ones should be fertilized. No other factors should be taken into account.

Question:

Does your clinic offer donor egg or embryo guarantees?

Answer:

We don’t believe in guaranteeing pregnancies because that’s not possible but our guarantees involve donor egg, embryo or IVF programs. If you are not pregnant after 3 cycles, we refund 100% of the money, so it’s a guarantee. A refunding guarantee—that’s what we offer. That’s how we commit to our patients.

Question:

Is it recommended to do PGS in the case of egg donation?

Answer:

In the first instance, unless there is some kind of pathology or problem, it is not necessary because the donors have stayed in Vistahermosa clinic and screened genetically and we do a parallel of lots of genes so it makes no sense. Or maybe the sperm is altered or the FSH is altered but not because of the donor.

Question:

I’m planning a second IVF with my own eggs. What if it fails? Should I keep trying with my own eggs? I’m 32. Is the egg quality the most important?

Answer:

Being 32, you should try at least until you have had 3 cycles as you are very young so you have the eggs but you also you have the age, which is an important factor. What we recommended is to use time lapse in every case so that we can check that the development of those embryos is improving and always do the transfer around day 5 because we have a more advanced embryo. So, the implantation rate could be better and we could control the quality of the transfer. Most centres do the transfer around day 3. We highly recommend doing it on day 5 because from day 3 to day 5 we get much more information so if we transfer two days before, we miss that information if we don’t have so many details about what we are transferring.

Question:

What documents does the patient need to provide for the first exam/meeting with the doctor?

Answer:

It depends, but normally it’s your medical history, an ultrasound scan and a transfer test to avoid any problems during the embryo transfer and, if you have a partner, ask him for an analysis if possible—DNA fragmentation and FISH (semen analysis)—and for both of you etiology, which are your viral tests, and the karyotype also to check if you are chromosomally normal. We could send you this in an email if you want to have it.

Question:

Is it normal to prescribe Levothyroxine if you don’t have an underactive thyroid?

Answer:

Not necessarily. But this is something personal for each clinic or doctor but normally it’s not very common.

Question:

Do you still accept patients in December? Do you close for the Christmas break?

Answer:

We are a hospital. We never close. We are always open, Christmas, summer, so patients are welcome when they need it. We are open 365 days, 24/7.

Question:

I have been told that as I am over 50 I have a much higher chance of miscarriage. What is your opinion?

Answer:

Here there are several factors. For someone over 50, the technique could be egg donation for sure. If you have a partner, we should also check how old he is and the sperm quality, and evaluate all the issues. We should also look at how you feel, your body mass index, your health and some other things before going ahead.

(Elaboration on the question): the patient would use donor eggs and donor sperm.

We should check your body mass index, your physical condition because you are at the age limit for treatment. If we could do it, we need to be sure that we can help you and we could transfer one good blastocyst but only one. This is mainly to protect you because a pregnancy at fifty years of age can be quite dangerous.

Question:

How do you determine when I’m ready for the embryo transfer
(with an egg donor)?

Answer:

When you have a triple line in the endometrium. When you have a trilaminar in the endometrium and the thickness is over 7 millimetres.

Question:

Do you do Skype consultations?

Answer:

Yes, we do Skype consultations every day except Sundays, so that could be possible. We are quite flexible about the working hours, too.

Question: If so, how much does it cost?

Answer:

Normally it costs 50 euros but for the webinar patients it’s free.

The presenting clinic

Here you can read more about PreGen-UR Vistahermosa reproduction unit: transparency, quality, and professionalism at lower costs. Watch another webinar presented by Dr. Sanchez from UR Vistahermosa.

#IVFWebinars are brought to you with the help of our Partners:
Eizellspende.de
Donor Conception Network UK

About the Author

Juan Manuel Moreno García

Juan Manuel Moreno García

Dr. Juan Manuel Moreno García has a degree in biology from the University of Alicante, Master’s degree in Human Reproduction and Human Reproductive Biology, has completed postgraduate courses in Obstetrics and Gynecology at the University of Valencia. Dr. Juan is also Semen Analysis Specialist and has been awarded numerous diplomas by ESHRE and the Association for the Study of Reproduction Biology (ASEBIR). Director of the Embryology Laboratory at the Reproduction Unit of Clínica Vistahermosa in Alicante. Dr. Juan Manuel Moreno García is a Director of the Embryology Laboratory at the Reproduction Unit of Clínica Vistahermosa in Alicante. Dr Moreno is a Member of Scientific Associations: Spanish Association of Biologists (COB), Association for the Study of Reproduction Biology (ASEBIR), Spanish Fertility Society (SEF), Spanish Society of Andrology (ASESA), European Society of Human Reproduction and Embryology (ESHRE).

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