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Donor egg IVF success rates – the truth clinics don’t tell you

Please note that the information contained on this site was correct at the time it was posted. We are as diligent as possible in updating the information on this website. While we constantly strive to provide quality information, please be aware that there may have been subsequent changes which make the information outdated at the time you are accessing it.

If you are looking for a clinic to have IVF treatment with donor eggs and you are wondering what IVF donor egg success rates are, read our article. While analysing the Internet forums, it can be easily seen that most patients searching for a clinic ask two important questions:

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  1. What is the IVF donor egg success rate?
  2. What is the cost of the treatment?

Let’s focus on the first one – donor egg IVF success rates. If you ask the first question on an Internet forum, you will get one of two answers, either, “very good – success!” and “not good – failure!” Unfortunately, such information will not make choosing the fertility clinic any easier. Internet forums can be a good source of content-related knowledge, but unfortunately understanding of the underlying meanings of IVF donor egg success rates, the ability to read the statistics published by the clinics, and, indeed knowing what to pay attention to – all require something more than a simple “success” or “failure.” So is there anything related to IVF success rates with donor eggs that clinics don’t want to tell you? Yeah… there are many things clinics won’t tell you – the fertility sector is very competitive and clinics are sensitive to sharing information they feel might benefit another clinic! They know what the patient is looking for (we know that) – it is the IVF success rate and this rate can be promoted in different ways which can, in turn increase its value.

Success rates with donor eggs in IVF – what do statistics mean?

Donor egg success rates indicate the percentage of treatment effectiveness in IVF with donor eggs; the percent of effectiveness or what number of patients after treatment (1 IVF cycle) become pregnant or (depending on the presentation method) give birth to a child. Such data is usually presented as one, the same percentage regardless of the age of the woman. For example, if the efficacy value is 51%, which means that 51 patients in 100 who are treated will get pregnant (or give birth) depending on how the statistic has been calculated.

Does the Donor Egg IVF Success Rate depend on a woman’s age?

In the case of treatment with a donor’s oocytes, the age of the woman is not very important. In short, donor egg IVF success rates will be more or less similar for each patient’s age group.

Below we present examples of egg donation success rates, including women’s age, developed on the basis of the SART Predictor – IVF calculator. SART Predictor uses a very large database of cycles: almost 500,000 IVF cycles in the US since 2006. After entering the appropriate values into the IVF Calculator – when we change only the age of the woman, over 45 years of age, the statistics on average decrease by one percent for every one year of life.

The following results apply to live births and not pregnancy rates per transfer, so this is the most important information about treatment statistics that a patient can receive.

IVF with donor egg success rates was developed for individual age groups of women, with the following assumptions:

  • The cause of infertility: Diminished Ovarian Reserve
  • Woman’s height, weight: 1.65 m, 69 kg
  • Prior pregnancies: No.
Egg donor IVF success rates – probability of live birth per woman age

Does the IVF with Donor Egg Success Rates depend on woman’s age?

 

Donor egg IVF success rates – fresh eggs vs frozen eggs

Many patients are wondering whether it is better to use a programme with fresh or frozen eggs. The Pros and cons have been explained above, but the latest available statistics also merit attention. Below we present the results of the success rates of such programmes, including:

  • Fresh donor eggs / pregnancy
  • Fresh donor eggs / live birth
  • Frozen donor eggs / pregnancy
  • Frozen donor eggs / live birth

The data was developed based on the CDC (Centers for Disease Control and Prevention) 2015 report. Data is not presented per patient’s age because according to the CDC, the differences between the success rates in a particular patient’s age range are minimal.

“All ages are reported together because previous data show that patient age does not materially affect success with donor eggs.”
CDC – 2015 Assisted Reproductive Technology, Fertility Clinic Success Rates Report

As shown in the chart below, for IVF with donor eggs – fresh cycle – donor egg success rate is on average 65.9%; a clinical pregnancy and live birth being 55.6%. It means that the success rate for live birth is approximately 10% less than the pregnancy rate. The IVF programme with donor eggs – frozen cycle – donor egg success rate is 52.3% with clinical pregnancy and 42.3% – live birth. Also, in this case, the value of success rate – clinical pregnancy should be reduced by approximately 10%.

IVF with egg donor – success rate of transfers with fresh and frozen eggs

IVF with donor eggs success rates – fresh eggs vs frozen eggs – per embryo transfer – preganancy vs live birth comparision

How successful is IVF with donor eggs? – the Pregnancy Funnel

Do you know that if you are reading this article and you are planning to have IVF treatment with donor eggs, you have an average (watch the video and see below):

  • 80% chance
    that after the egg fertilization you will receive properly developing embryos
  • another 75-85% chance
    that the embryos transferred to your uterus will implant correctly
  • another 70-80% chance
    that you will be diagnosed with biochemical pregnancy (1 week after the embryo transfer)
  • another 55-65% chance
    that you will be diagnosed with clinical pregnancy – 12-week ultrasound scan
  • and finally – about a 45-55% chance
    of having a live birth.

This means that on average 1 in 2 women having IVF treatment with donor eggs will have a baby. This can be linked to many factors. However, bear in mind that when you have a second round of treatment, your chances grow. Are you curious why this is so? Let’s start from the beginning.

IVF with donor eggs success rates - Pregnancy Funnel

How successful is IVF with donor eggs?

 

7 things you need to know about the donor egg IVF success rates

  1. Statistically, in IVF with a donor eggs programme, success rates are not dependent on the recipient’s age.
    This means that regardless of your age, if you are able to become pregnant and carry to term, your chances for bearing a baby will be, on average, the same as in women of different age. That is why looking for a fertility clinic which shows the statistics by patient’s age can be misleading.
  2. On average about 20-30% of miscarriages occur before the 12th week after IVF treatment.
  3. There is no standardized method for presenting egg donor statistics.
    IVF clinics apply various methodologies in calculating their success rates and do not always give information on how the statistics have been derived.
  4. Most often, in vitro clinics present data related to the success rate based on a percentage of clinical pregnancies (at 6 weeks) per embryo transfer.
    This data does not include miscarriages occurring between 6th and 12th week of pregnancy.
  5. It is rare for fertility clinics present data related to the success rate of IVF with donor eggs based on the percentage of births of healthy babies.
    This type of statistics will always be lower. Some in vitro clinics are not able to monitor the patient over a longer period of time, so they simply do not have such data.
  6. Statistics of healthy baby births from egg donor programmes is on average 10-20%.
    Lower than the percentage of clinical pregnancies (at 6 weeks) achieved per embryo transfer. These are real statistics from which you can learn what your chances are for having a baby.
  7. Clinics do not reveal details and statistics regarding the donor.
    Age is not a factor here. More relevant is, for example, if the donor has previously had a healthy baby.
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IVF clinics’ methods of presenting the statistics for IVF with donor egg success rates – using marketing techniques

  1. Pregnancy per patient’s cycle
    This type of statistic is very rarely presented by fertility centres. Statistically, the results of such a presentation will be the lowest. This stems from the fact that an egg recipient’s cycle may not be completed due to, for example, poor quality of embryos or no fertilization.
  2. Biochemical pregnancy per embryo transfer
    Biochemical pregnancy is diagnosed based on laboratory examination, usually 1 week after embryo transfer. This type of statistic is often used by in vitro clinics precisely because it shows very good results. It does not include cases with failed embryo transfer and only includes successful embryo transfers. Also, pregnancy is diagnosed 1 week after transfer so later miscarriages are not taken into account.
  3. Clinical pregnancy per embryo transfer at 6 or 12 weeks of pregnancy
    Clinical pregnancy is diagnosed based on laboratory blood tests and ultrasound at 6 or 12 weeks. The most often presented results refer to pregnancies diagnosed at 6 weeks. The ultrasound shows a visible gestational sac in the uterus. Here, the statistics are better than those for 12 weeks. Again, they do not include any miscarriages occurring at 6-12 weeks.
  4. Live birth – take home baby
    The statistics of giving birth to a healthy baby after IVF treatment with donor eggs are very rarely presented.
    These are the lowest of all the statistics. Often fertility centres do not know if pregnancy ended in a live birth and baby because they are not able to monitor a patient over such a long period of time.

IVF Cumulative pregnancy rates or cumulative live birth rates…

Nowadays more and more clinics publish cumulative success rates for the ivf treatments performed at their facilities. For this reason, we have prepared a separate article regarding the topic. If you are a patient who is searching for a clinic to undergo IVF treatment, then “donor eggs IVF success rate” is one of the factors to be taken into consideration in your research.

“Cumulative success rate” indicates the percentage of patients who have successful treatment (got pregnant) after few cycles performed at the clinic (it is usually 3 attempts). It’s important to know how to read data provided by the clinic regarding the “success rate”.

Why do some of IVF clinics decide to provide the information about success rates with donor eggs in IVF this way? What are the methods of calculation? Is there a marketing catch or is there medical justification for such publications?

You may be interested in reading: Cumulative pregnancy rates or cumulative live birth rates – what do they mean?

What exactly impacts the success rate of IVF with donor eggs?

  1. The quality of the donor’s eggs
    The quality of donor eggs greatly influences IVF success rates. Donors are usually aged 18-35, with the qualifying age differing in various countries. In some countries, you can qualify if you are aged 19-20 but below 30. The best eggs the clinics receive are those coming from donors who have had at least one baby before. It is thought that such eggs have a greater potential. However, donors like this are scarce. Other qualifying factors are also important: age, AMH level, infection tests or genetic tests, e.g. karyotype analysis. Acquiring a qualified egg donor is extremely expensive, often constituting half of the cost of the whole programme. That is why skipping some qualification factors, can be tempting for some in vitro clinics if they want to save money. All of this can result in lower egg quality.
  2. Experience and quality of IVF laboratory
    The experience of the team of embryologists and the quality of the laboratory are crucial factors which influence the donor egg IVF success rate. This is true not only in cases of egg donation but also in IVF programmes with own eggs.
  3. IVF procedures in the IVF laboratory
    There are many IVF techniques which can be used in different scenarios based on medical history of the patient and any medical indications. Many of them can increase success rates such as ICSI, AH – assisted hatching, blastocyst culture & embryo transfer on day 5, PGS – preimplantation genetics screening and so on. There are also techniques which are recommended for male factor infertility such as IMSI, PICSI. Remember that male factor infertility may be the case on average in 40-50% of IVF programmes unless you use the sperm from a donor.
  4. Your and your partner’s medical condition
    Bear in mind that donor’s eggs take the place of your eggs which may be scarce, or of insufficient quality. However, there is an additional factor that can influence the egg donor IVF success rate – it is your partner’s genetic material and the quality of his sperm. Make sure your partner has had all the necessary medical tests: sperm analysis, sperm DNA fragmentation test and, most of all, genetic tests, e.g. karyotype analysis. It can happen that, in addition to donor eggs, you may have to consider using donor sperm as well. Statistically, according to CDC (National Center for Chronic Disease Prevention and Health Promotion) – about 36% of IVF programmes are carried out because of the “male factor” –  that is because of issues on the partner’s side. However, the data is based on all IVF cycles performed – autologous and donor egg cycles. According to IVF centres we work with, and our own data for IVF with donor eggs cycles about 40% to 55% of patients are struggling with “male factor” related issues.
  5. …and most importantly – your attitude
    We keep meeting patients who say they are looking for a clinic which they will visit only once, for a maximum for 2-3 days, to have the embryos transferred. They claim they do not have time to travel that much and some of them mention the financial limitations. A positive, realistic attitude to treatment puts you on the road to success.
    Fast, cheap treatment does not necessarily lead to successful treatment and is more often mutually exclusive. If your clinic claims otherwise, think if this is really what you expect. Some elements of the process, like getting to know the patient, direct patient-doctor contact cannot always be replaced by an e-mail or a Skype call.The correct, minimal medical process should involve a good quality initial consultation with the doctor, who will check if there are no contraindications for pregnancy, regardless of the fertilization method. The doctor needs to look at both you and your partner’s medical histories to check that nothing has been overlooked. While embryo transfer is not a complicated procedure, you should stay somewhere near the IVF clinic, at least for the evening before and for the day of the transfer. If possible, fly the day after the transfer. Try to avoid any stressful situations and activities during your fertility treatment.

If you are wondering how to increase the donor egg success rate – you may watch the webinar with Dr Pilar Alama. Dr Alama explains all you need know about IVF donor egg success rates and answers the most popular questions: All you need to know about success rates of IVF with donor eggs

The statistics of success rates of IVF with donor eggs – the USA, the UK, and Spain

Below you will find the statistics published by SART (the USA) – 2014, SEF (Spain) – 2014 and, HFEA (the UK) – 2013. The data includes over 90% of in vitro clinics from each country. Unfortunately, some data is not available in certain countries. The statistics refer only to IVF cycle with fresh donor eggs.

 USASpainUK
Clinical pregnancies (6th week)66.8%55.6%no data
Live births56.8%48.3%32%

It is worth mentioning that in the case of Spanish statistics, the data may not be complete. This is because of the fact that in Spain, just like in many other European countries, there are many egg donation programmes run for foreign patients. Unfortunately, in most cases monitoring the results of such programmes can be difficult.

Below you will find detailed statistics published by SART – USA for 2014 with data specifying fresh eggs and frozen eggs IVF cycles

 IVF with fresh donor eggsIVF with frozen donor eggs
No. of IVF cycles850711974
No. of transfers725611155
Avg. no. of embryos transferred1.71.6
Clinical pregnancies (6th week)66.8%51.7%
Live births56.8%41.5%

The statistics offered by the best IVF clinics in Europe are as good as those in the USA. Many fertility centres have a higher success rate than the average rate in the USA.

Types of donor egg programs:

  1. Programme with fresh donor eggs – fresh eggs transfer. The whole programme is carried out in a synchronized cycle of the donor and the recipient.
    The success rate of IVF with donor eggs: optimal
  2. Programme with fresh donor eggs – frozen eggs transfer – the embryos are frozen using vitrification and transferred to the recipient during the next treatment cycle.
    The success rate of IVF with donor eggs: optimal
  3. Programme with frozen donor eggs – the donor eggs are frozen and placed in an egg bank. After thawing, fertilization is carried out and fresh embryos are transferred to the recipient’s uterus.*
    The success rate of IVF with donor eggs: good – to be confirmed, see below

*In the case of frozen egg donor programmes, there are statistics indicating that the success rate of IVF with donor eggs is just a touch worse than in a fresh treatment cycle. The role played here by the IVF laboratory and the specialists’ experience in egg cryopreservation is crucial, as eggs are very delicate. The freezing and thawing process is much more difficult than with embryos. The average survival rate of frozen eggs from women under 32 is more than 90%. However, these statistics come from clinics specializing in this type of procedure and have relevant experience. Bear in mind that these are not the statistics of egg donor success rate but only the survival rate of the eggs.

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If you are looking for an egg donation clinic abroad, use the eggdonationfriends unique patients tool – Clinic Matching Test. We analyse your needs and choose 3 overseas clinics which match your expectations. Our database of IVF centres includes only trusted fertility clinics which have experience in providing high quality services to international patients. The suggested IVF centres will contact you directly within 3 working days. Spare 3 minutes of your time – you will save at least a few hours! Our assistance is free of charge.

We are also happy to advise if you have already chosen IVF clinic abroad. The consultants from eggdonationfriends will be able to help you through any concerns you may have and maximise your chances of getting a positive outcome from your infertility treatment. It is understandable that you want the best IVF treatment in the world.

We have a broad database of trusted egg donation clinics in Europe, including Spain, Czech Republic, Ukraine, North Cyprus, Greece, Russia, Poland and more…

EggDonationFriends recommendations

Other resources regarding IVF & Success rates:

The success rate of IVF with donor eggs which is presented by fertility clinics should never be your most important choice criterion.
Take ivf with donor eggs success rates with a pinch of salt. Always ask questions about the clinic’s methodologies for deriving statistics.
Renowned, experienced fertility clinics have similar success rates of egg donation. The success rates are higher than in IVF clinics with little experience.
Experienced clinic – is a clinic which runs at least a few hundred IVF treatments with donor eggs a year. The best-case scenario is when the clinic does at least 10 programs a month per each doctor.
The success rate mostly depends on donor egg quality and donor qualification methods.
Good communication, patient care, customized treatment will give you more than good statistics which you can find on the clinic’s website.
Be wary of success rates of egg donation on Internet forums. This information is always black & white, either success or failure. Ask about the treatment quality, doctors’ experience, post-op care or emergency contact options.
Your attitude towards treatment is the key to success i bear in mind: you cannot treat an infected tooth over the phone. The same way you cannot treat infertility during one visit or over the phone.
Article sources

16 Comments

  1. I’m 41. I thought age of egg donor and success rate are somehow linked. For me it’s important the donor is young and healthy.

  2. even I would like to know the difference between frozen eggs and fresh eggs. Does that affect fertility? which one is better??

    • Dear Maria, a fresh donor egg cycle is when the patients is working with a selected donor of their choice. In this case, you get all the eggs from her cycle. If the doctors retrieve 25 eggs from the donor, you can use all those eggs now or later on. If in the cycle they get only 8-10 eggs, this is what you get to work with.
      A frozen egg treatment cycle is when you or the clinic get a lot of eggs from an egg bank. The eggs are then fertilised. You usually get a batch of 6 eggs no matter how many were retrieved. If there were 26 oocytes collected, these eggs will be distributed to different recipients. Out of these 6 eggs you get only 4 might get fertilised, as you can see the numbers are low. This is just an example but can show you how it works.
      The decision is entirely up to you. You should take all factors into consideration.

  3. It’s great article – an maybe not all clinics would find it useful (and would be happy….on that) as it shows some markteting techniques used to hide inconvenient information…. for patients…
    Anyway as far as ivf success rates are concerned there should be cumulative rates subject covered as it seems to be more often used by clinics. Well it’s understable – the higher is better… As I saw 93% ivf egg donation success rate on one of the websites….. it turned out it was cumulative ivf success rate – counting patients who undertook 3 ivf cycles in a row – so that’s cumulative rate…..

    • Thank you, Susan, for your comment. Actually we are working on an article covering cumulative success rates in IVF with donor eggs treatment. It will be published soon. Follow us on Facebook to get the updates about our new articles.

    • Definitely good point about cumulative ivf egg donation success rates. The subject is weird adn difficult to understand as some clinics show the cumulative rates only….

    • Why use cumulative ivf success rates? Does it matter for ivf with donor eggs as egg donation treatment is independent of woman’s age…?

    • Dear Sushmita, if you suffer from premature menopause, egg donation treatment might be for you. After running tests, your fertility doctor will be able to choose the right course of treatment. If you wish to find the best clinic for you, contact us at patient@eggdonationfriends.com and we will help find an IVF clinic that is best for you.

  4. To find the most reputable clinic, Dr. Levine says women should do some research to find out who does the best IVF treatments.  Levine recommends going to the  CDC s published fertility rate reports, calling up the best clinics, and telling them you d like to become a donor. Regardless of if you want to donate your eggs through a clinic or an agency, you can still call up clinics and see which agencies they work with. Purcell also recommends asking the clinic about possible risks and what are those risks at that particular clinic. We could give overarching risks but then what are the risks at your fertility clinic: How many cases of infection, or bleeding, or OHSS do you see in a year? Dr. Devine says that one of the first questions any potential egg donor should ask going into a clinic is if that clinic adheres to ASRM guidelines, since they re there for a reason.

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